منابع مشابه
Do Market Incentives Crowd Out Charitable Giving?
Donations and volunteerism can be conceived as market transactions with a zero explicit price. However, evidence suggests people may not view zero as just another price when it comes to pro-social behavior. Thus, while markets might be expected to increase the supply of assets available to those in need, some worry such financial incentives will crowd out altruistic giving. This paper reports l...
متن کاملReaching out for signals
ErbB1 receptors situated on cellular filopodia undergo systematic retrograde transport after binding of the epidermal growth factor (EGF) and activation of the receptor tyrosine kinase. Specific inhibitors of the erbB1 receptor tyrosine kinase as well as cytochalasin D, a disruptor of the actin cytoskeleton, abolish transport but not free diffusion of the receptor-ligand complex. Diffusion cons...
متن کاملSorting out Toll Signals
Upon recognition of microbial products, Toll-like receptors (TLRs) recruit distinct combinations of adaptors to induce TLR-specific gene expression. In this issue, Kagan and Medzhitov (2006) demonstrate that the adaptor TIRAP/Mal localizes to the plasma membrane by binding to phosphatidylinositol 4,5-bisphosphate (PIP2). This binding recruits a key adaptor MyD88 to TLR4, suggesting that there i...
متن کاملMicroRNA dissects out dangerous pancreatic cysts from all the rest.
Malignant transformation of pancreatic cysts occurs in only a fraction of patients. The diagnostic dilemma is identifying which cysts pose a cancerous threat. Cyst fluid has been analyzed in a variety of ways to answer this question but the microRNA (miRNA) profile of the fluid may finally hold the answer.
متن کاملGiving up on child psychotherapy: who drops out?
Some critical comments are offered with regard to the use of the designation psychotherapy dropout in the article by Weisz, Weiss, and Langmeyer (1987). It is proposed that individuals who do not begin a course of psychotherapy should not be viewed as dropouts. Reference is also made to problems of generalization.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature Reviews Neuroscience
سال: 2008
ISSN: 1471-003X,1471-0048
DOI: 10.1038/nrn2383